The association between triglycerides/high-density lipoprotein cholesterol ratio, insulin resistance, and serum androgen levels in patients with polycystic ovary syndrome

Objectives: Insulin resistance and dyslipidemia are common comorbidities of polycystic ovary syndrome. We aim to evaluate the association between triglycerides/high-density lipoprotein cholesterol ratio, insulin resistance, serum androgen levels in patients with Methods: enrolled a total 40 syndrome 20 healthy control subjects this cross-sectional study. The were divided into two subgroups obese non-obese. ratio homeostatic model assessment calculated for all individuals. Demographic characteristics, metabolic parameters, androgens compared study subgroups. P-value < 0.05 was accepted as statistically significant. Results: higher than other groups (3.64 ± 3.06 vs. 1.07 0.36 1.18 0.53 non-obese group, p 0.005). positively correlated (r=0.546, 0.001), testosterone (r=0.402, = 0.010), free index (r=0.609, 0.001) while negatively sex hormone-binding globulin (r=-0.497, 0.001). Obese had levels, index, lower (0.71 0.49 ng/mL 0.45 0.16 ng/mL, 0.006; 3.1 1.91 1.01 0.49, 0.005; 26 10.3 nmol/L 59.6 43.7 nmol/L, 0.005, respectively). also worse lipid including high triglycerides low high-density when groups. Conclusions: androgenic hormonal profiles